Meta Pixel Code

Bimatoprost ophthalmic solution 0.03% (Latisse®) is the only FDA-approved prescription treatment for eyelash hypotrichosis, clinically proven to enhance eyelash length, thickness, and darkness through stimulation of the hair growth cycle. Since its approval in 2008 (FDA NDA #022231), Latisse® has become the standard of care for patients seeking medical management of inadequate eyelashes, with safety and efficacy established in multiple randomized controlled trials. At Cosmetic Injectables Center Medspa in Sherman Oaks, all Latisse® consultations and prescriptions are overseen by board-certified physician Dr. Sherly Soleiman, MD, ensuring expert guidance and patient safety throughout the treatment process.

Latisse For Eyelash-Hypotrichosis

What Is Eyelash Hypotrichosis?

Eyelash hypotrichosis refers to inadequate or insufficient eyelashes, characterized by reduced length, thickness, or darkness. This condition can be congenital, acquired, or age-related, and often impacts self-confidence and ocular protection. Dr. Sherly Soleiman, MD, board-certified physician and national trainer in medical aesthetics, leads the certified experts at Cosmetic Injectables Center Medspa in providing evidence-based solutions for eyelash enhancement.

Bimatoprost (Latisse®): Mechanism and FDA Approval

Bimatoprost is a prostaglandin analog originally developed to lower intraocular pressure in glaucoma. Its cosmetic application emerged after patients reported increased eyelash growth during glaucoma treatment. Bimatoprost (Latisse® 0.03%) is FDA-approved for treating eyelash hypotrichosis, enhancing eyelash length, thickness, and darkness by prolonging the anagen (growth) phase of the hair cycle through prostaglandin receptor agonism (FDA Approval Letter).

Clinical Efficacy: What Do the Studies Show?

Eyelash Growth and Density

Multiple clinical trials and reviews confirm that Bimatoprost significantly increases eyelash length (average 25% after 16 weeks), thickness, and pigmentation (StatPearls Review, NCBI). In a foundational study, 78% of users achieved at least a one-grade improvement in eyelash prominence after 16 weeks (2010 Review, PMC). Histological studies demonstrate increased follicle size and anagen-phase hairs, supporting the mechanism of follicle stimulation (2019 Histological Study, PMC).

Eyebrow and Off-Label Hair Growth

Recent prospective trials show that Bimatoprost also improves eyebrow density and length, with a 70% improvement in density after 5 weeks compared to 30% with placebo (2024 Clinical Trial). While not FDA-approved for eyebrows, the mechanism is similar.

Duration and Maintenance

Eyelash improvements are typically observed after 8–16 weeks of daily application. Discontinuation leads to gradual return to baseline over several weeks (NCBI StatPearls). No long-term maintenance effect persists after stopping treatment.

Safety Profile and Side Effects

Bimatoprost is well-tolerated in cosmetic use. The most common side effects are mild and reversible, including conjunctival hyperemia (up to 45%), eyelid skin darkening, and ocular irritation. Iris pigmentation changes are rare but may be permanent. Lower-concentration formulations (0.01%) reduce side effect incidence (StatPearls Review). No systemic cardiovascular effects have been observed in clinical trials.

Regulatory Status and FDA Guidance

Latisse® received FDA approval in 2008 for eyelash hypotrichosis. The approval required postmarketing studies in pediatric and African American populations to confirm safety and efficacy (FDA Approval Letter). The FDA warns against contamination risks and highlights the potential for eyelid and iris pigmentation changes.

Mechanism of Action: How Does Bimatoprost Work?

Bimatoprost acts as a prostaglandin F2α analog, binding to prostaglandin receptors in hair follicles. This interaction prolongs the anagen phase, increases follicle size, and stimulates melanogenesis, resulting in longer, thicker, and darker eyelashes (Mechanistic Review). Histological studies confirm increased matrix activity and dermal papilla thickness without new follicle generation.

Alternatives to Bimatoprost (Latisse®)

Several alternatives exist for individuals seeking eyelash enhancement. These include other prostaglandin analogs (off-label), peptide-based serums, and cosmetic options such as extensions or tinting. Only Bimatoprost (Latisse®) is FDA-approved for eyelash hypotrichosis. The table below compares available options:

Eyelash Enhancement Options: Comparison Table

Treatment FDA Approved for Eyelash Growth Active Ingredient Mechanism Typical Results Common Side Effects Duration of Effect Internal Link
Latisse® (Bimatoprost) Yes Bimatoprost 0.03% Prostaglandin analog ↑ Length, thickness, darkness (8–16 wks) Hyperemia, eyelid pigmentation, rare iris pigmentation Reversible after stopping Latisse Procedure
Prostaglandin Analog Serums (off-label) No Latanoprost, Travoprost, etc. Prostaglandin analog Similar, less studied Similar to Latisse Reversible N/A
Peptide-Based Serums No Peptides, vitamins Peptide signaling Modest improvement Minimal (irritation) Reversible N/A
Eyelash Extensions No Synthetic fibers Cosmetic only Immediate, temporary Allergic reaction, lash loss Until removed N/A
Eyelash Tinting No Dye Cosmetic only Darker lashes Allergic reaction 4–6 weeks N/A

Who Is a Candidate for Latisse®?

Candidates include adults with inadequate eyelashes due to genetics, age, or medical conditions. Latisse® is not recommended during pregnancy or for individuals with certain eye conditions. A consultation with a certified provider at Cosmetic Injectables Center Medspa ensures a thorough evaluation and informed consent.

Application Protocol and Patient Experience

Latisse® is applied nightly to the upper eyelid margin using sterile applicators. Results are typically visible within 8 weeks, with full effect at 16 weeks. Ongoing use is required to maintain results. All patients at Cosmetic Injectables Center Medspa receive comprehensive instructions and safety guidance under Dr. Soleiman’s supervision.

Off-Label and Investigational Uses

Bimatoprost is under investigation for other hair growth indications, including eyebrow hypotrichosis and alopecia. Early studies show promising results for eyebrow density and hair regrowth in vitiligo-associated hypotrichosis (2024 Systematic Review), but these uses are not FDA-approved.

Safety, Informed Consent, and Medical Oversight

Patient safety is prioritized at Cosmetic Injectables Center Medspa. All patients receive a Good Faith Exam and full disclosure of risks, benefits, and alternatives. Dr. Soleiman and her certified team adhere to strict protocols to minimize side effects and ensure optimal outcomes.

Related Nonsurgical Cosmetic Procedures

Patients interested in eyelash enhancement may also benefit from other nonsurgical medical aesthetic procedures, including:

Frequently Asked Questions

What is Bimatoprost (Latisse®) used for?
Bimatoprost (Latisse®) is FDA-approved to treat eyelash hypotrichosis by increasing eyelash length, thickness, and darkness.
How long does it take to see results with Latisse®?
Most patients notice longer, fuller lashes within 8 weeks, with maximum results at 16 weeks of nightly use.
Are the effects of Latisse® permanent?
No. Eyelash improvements gradually return to baseline after discontinuing Latisse®.
What are the most common side effects of Bimatoprost?
The most common side effects are mild redness, eyelid skin darkening, and occasional eye irritation. Rarely, iris color may darken.
Is Latisse® safe for everyone?
Latisse® is not recommended during pregnancy or for those with certain eye conditions. A medical evaluation is required before use.
Can Bimatoprost be used for eyebrow growth?
While not FDA-approved for eyebrows, studies show Bimatoprost can increase eyebrow density and length.
What happens if I stop using Latisse®?
Eyelashes will gradually return to their original appearance over several weeks to months.
How is Latisse® applied?
Latisse® is applied nightly to the upper eyelid margin using a sterile applicator. Lower lashes are not treated.
Are there alternatives to Latisse®?
Alternatives include other prostaglandin analog serums (off-label), peptide-based serums, eyelash extensions, and tinting.
Where can I get Latisse® in Los Angeles?
Latisse® is available by prescription from certified providers at Cosmetic Injectables Center Medspa in Sherman Oaks, serving the greater Los Angeles area.