Hylenex and Vitrase Sherman Oaks
Hylenex and Vitrase (two of the most common brands of hyaluronidase enzymes in the USA) are enzymes used in aesthetic medicine to dissolve hyaluronic acid-based dermal fillers. They are valuable tools for managing complications or dissatisfaction with filler treatments, allowing for precise corrections and optimal results. Hyaluronidase enzyme breaks down hyaluronic acid in the filler, enabling the body to absorb and eliminate it efficiently.
What are Hylenex and Vitrase ?
Hylenex and Vitrase are enzymes that dissolve hyaluronic acid-based dermal fillers. Hyaluronidase enzyme use requires careful consideration of dosage, dilution, and patient-specific factors to ensure safety and effectiveness. The dosage typically depends on the volume and type of filler and the treatment area. For example, 1500 IU of hyaluronidase can dissolve 1-3 mL of filler. The enzyme is injected directly into the target area, and gentle massaging can help distribute it evenly and enhance its effectiveness.
Side effects such as swelling, bruising, redness, or allergic reactions may occur but are generally mild and temporary. As a prescription medication, Hylenex and Vitrase should only be administered by a qualified medically licensed aesthetic practitioner, ensuring the procedure is done safely and tailored to each patient’s needs and desired outcomes.
Types/Different Brands of Hyaluronidase
- Hylenex– a brand of hyaluronidase with lab-grown human DNA using Chinese hamster ovarian cells (less risk of reactions)
- Vitrase – bovine derived (relatively higher risk of reactions)
- Generic hyaluronidase compounded by a local pharmacy (source of ingredients depends on the pharmacy)
Hylenex and Vitrase Benefits
Both, Hylenex and Vitrase are enzymes approved by the FDA. Below you can read what you can expect from them.
What Results to Expect:
- Corrects Overfilled or Misplaced Fillers: Dissolves excess filler for a natural appearance.
- Treats Adverse Reactions: Resolves lumps, nodules, or swelling caused by improper filler placement.
- Reverses Filler Migration: Clears unwanted movement of fillers, particularly in areas like the lips or under the eyes.
- Resolves Vascular Complications: Safeguards against tissue damage by restoring blood flow in cases of vascular occlusion/blockage by hyaluronic acid fillers.
- Prepares for New Fillers: Removes residual filler to ensure a clean slate for future treatments.
- Quick and Safe Procedure: A minimally invasive solution with little to no downtime.
Didn’t get the results you wanted? At Cosmetic Injectables Center, we use advanced enzymes like Hylenex and Vitrase to safely and effectively dissolve misplaced fillers. Book your consultation today and let us help you restore your confidence!
How the Procedure Works
Hyaluronidase exams such as Hylenex and Vitrase target hyaluronic acid-based fillers by hydrolyzing the filler into smaller fragments. This allows the body to absorb and eliminate the material naturally. By injecting the enzyme into the treatment area with or without the use of ultrasound, and gently massaging the site, practitioners ensure even distribution and effective results.
Before & Preparation
- The dosage is tailored based on the type and volume of filler to be dissolved.
During the Procedure
- The area is cleaned and sterilized.
- Hyaluronidase is injected directly into the target area.
- Gentle massaging enhances distribution and effectiveness.
Aftercare & Recovery
- Expect mild redness, swelling, or bruising that resolves within hours to days.
- Avoid strenuous activity for 24 hours.
- Follow up with your provider as needed.
Treatment Areas
Hylenex and Vitrase are FDA-approved for the following treatment areas:
- Lips: Corrects unevenness, overfilling, or filler migration.
- Under-Eyes (Tear Troughs): Treats puffiness, lumps, or discoloration.
- Cheeks & Mid-Face: Resolves overfilling or asymmetry.
- Nasolabial Folds (Smile Lines): Addresses filler irregularities or abnormal puffiness/new lines.
- Jawline & Chin: Refines contours and corrects excessive volume.
- Nose: Resolves complications or overcorrection in non-surgical rhinoplasty.
- Forehead & Temples: Smooth out rare filler issues, lumps, and bumps, and can treat vascular compromise.
- Emergency Vascular Complications: Restores blood flow by dissolving occlusions.
Restore natural beauty with Hylenex® and Vitrase®—advanced technology to correct, refine, and enhance your filler results effortlessly.
Am I a Good Candidate for Hylenex and Vitrase?
You are a good candidate for Hylenex and Vitrase if you meet the following criteria:
- Have overfilled or uneven filler results.
- Experience lumps, nodules, or bluish discoloration (Tyndall effect).
- Face filler-induced vascular complications.
- Need residual filler removed before new treatments.
- Have realistic expectations and prioritize safety and natural-looking results.
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- Typical Age: over 18
- Weight: no weight restrictions
- Health Restrictions:
- It’s best to refrain from using any filler injectables or enzymes during pregnancy and breast-feeding.
- You also may want to avoid them if you have multiple allergies, or are allergic to bees (Vitrase).
Not a Candidate: Individuals with known allergies to hyaluronidase, using non-hyaluronic acid fillers, or with active infections should seek alternatives.
Hylenex vs Vitrase
Hylenex
FDA- Approved:
Source:
Allergic Reaction:
Common Use:
Vitrase
FDA- Approved:
Source:
Allergic Reaction:
Common Use:
Side Effects & Risks
Common side effects from Hylenex and Vitrase are:
- Mild Bruising
- Redness
- Swelling
These side effects are generally mild and temporary
Hylenex and Vitrase Reviews
”Let me start off by saying I used to think that it didn’t matter who did your injectables, I would look for a good deal and that’s where I’d be! So one day a girlfriend of mine recommended Dr. Soleiman, and let me tell you she completely change my mind!
First of all this lady is absolutely gorgeous, I just have to say that :), but she is a true artist with the needle. Your face never looks like you had anything done just pure rejuvenation. Her technique is beyond amazing! I recently accompanied a girlfriend for a procedure in Beverly Hills and as I watched the nurse I thought to myself this lady is just injecting and not looking at the bigger picture, not moving the needle around, so generic….. Dr. Soleiman would never do it like this! This experience just made me appreciate what she does even more. If you’re looking for someone to do a perfect job don’t waste your time trying to get a cheap deal and end up looking like a real housewife who can’t move their face lol, just see her! She is extremely down to earth, and truly goes the extra mile to stay educated in her industry! This review is from the bottom of my heart and I hope it helps you make the right decision!
I LOVE YOU DR. SOLEIMAN …… YOU AND YOUR STAFF ROCK!!! XOXO
I HOPE YOU KNOW HOW MUCH YOU ARE APPRECIATED!
P.S DON’T LISTEN TO ANY NEGATIVE REVIEWS (I THINK THERE ARE 2). …..I APPOLOGIZE ON THEIR BEHALF, THEY ARE JUST RETARDED! 🙂 ”
Advanced hyaluronidase solution at Cosmetic Injectables corrects overfilled or uneven results, restoring flawless, natural-looking contours.
Hylenex and Vitrase FAQ
What is Hylenex used for in aesthetics?
It dissolves hyaluronic acid-based fillers to correct overfilled areas, asymmetry, or complications like lumps or vascular occlusion.
Is Hylenex painful?
If a small amount is used or if numbing liquid (not just topical cream) is mixed with the reversal agent, the procedure should be comfortable. On the flip side, if larger amounts without lidocaine liquid are used in sensitive areas such as the lips, the procedure can feel like a short burst of burning sensation under the skin. The pain typically goes away after one minute.
Is Hylenex safe?
Yes, when administered by a qualified practitioner. Vitrase’s application may benefit from a skin test prior to use due to the higher risk of reactivity given it is bovine-derived. Hylenex has less risk of a reaction.
How do you remove hyaluronic acid from your face?
Hyaluronic acids can be removed by injecting an enzyme called hyaluronidase (brand names can be Hylenex or Vitrase) which breaks down the molecules that bond the hyaluronic acids together. Your body then disposes of the remains.
Are hyaluronic acid fillers reversible?
Yes, all of the FDA-approved, pure hyaluronic acid fillers in the USA are reversible through injection of hyaluronidase enzyme.
What is the downside of dissolving filler?
There are typically no downsides of reversing filler except that the skin goes back to its original position (for some that’s good, other not). Sometimes people forget what they looked like before the fillers and may regret reversal as they are used to their appearance with fillers.
When should hyaluronidase not be used?
Hyaluronidase should not be used if you are allergic to the substance, or if you’re happy with your filler results. Since there are no studies on pregnant women, we recommend holding off on reversals until after pregnancy and breastfeeding.
How long does the procedure take?
The procedure typically takes 1-10 minutes, depending on the treatment area and usage of ultrasound.
Does Hylenex work immediately?
Some results are visible instantly. However, it can take 24 hours for a complete breakdown of the injected hyaluronic acid. And another 1-2 weeks for everything to settle.
How long does it take for Hylenex to work?
Hylenex starts working immediately and most of its results are achieved by 24 hours.
Does hyaluronidase destroy natural tissue?
No, there have been no reliable studies showing that natural tissue is destroyed.
How do you inject Hylenex?
Hylenex comes as a liquid in a vial, ready for injection if necessary. The liquid is drawn into a syringe and injected directly into the area of interest with a very small needle.
What are the common side effects?
Mild swelling, redness, or bruising at the injection site are the common side effects of Hylenex and Vitrase and they typically resolve within a few days
Can Hylenex dissolve all types of fillers?
No, it only works on hyaluronic acid-based fillers. Other types require alternative approaches.
How soon can I get new fillers after Hylenex?
We suggest waiting at least 1-2 weeks to allow full healing and resolution of any swelling.
Does Hylenex dissolve filler?
Yes, one of the most common uses of Hylenex is to dissolve Hyaluronic acid fillers. It does not work much on other types of fillers such as PLLA (ie Sculptra) or calcium hydroxyapatite (ie Radiesse).
How much does Hylenex cost?
Hylenex can cost anywhere between $100 to $600 per treatment depending on the amount and type of fillers being reversed. Some fillers take several sessions.
What is the difference between Hylenex and hyaluronidase?
Hylenex is a name-brand type of hyaluronidase. Another brand is Vitrase but is ovine-derived which can have a higher risk of reactions.
Will my face go back to normal after hyaluronidase?
Yes, your body will release hyaluronic acids until it reaches its naturally determined concentration for your age.
Is Hylenex FDA approved?
Yes, Hylenex has passed safety studies and has received FDA approval, but not specifically for filler reversal. However, it is used very commonly and safely for this purpose.
What is the downtime for Hylenex?
There’s typically no downtime for Hylenex unless you bruise, which can take 1-2 wks. We have a bruise laser that can treat bruising. Also, be prepared to undergo a day or two of “dehydrated skin” appearance while your skin regenerates new hyaluronic acids.
What can go wrong with hyaluronidase?
There are typically no side effects with Hyaluronidase unless you have an allergic-type reaction to it, bruise, or if it’s not injected into the correct area to achieve the desired outcome. In that case, either more Hyaluronidase filler can be injected to tweak the final result.
Target unwanted filler with precision. Hylenex® and Vitrase® offer quick, non-invasive solutions for refreshed and perfected skin at Cosmetic Injectables Medical Spa