Xeomin and Botox are two of the most widely used injectable neurotoxins for reducing dynamic facial wrinkles. Both are FDA-approved and offer effective, temporary improvement in frown lines and other expression-related wrinkles. Understanding the differences and similarities can help you make an informed decision about your treatment options.
What Are Xeomin and Botox?
Both Xeomin (incobotulinumtoxinA) and Botox (onabotulinumtoxinA) are purified forms of botulinum toxin type A. They work by temporarily relaxing targeted facial muscles, smoothing wrinkles caused by repeated expressions.
- Xeomin: FDA-approved for glabellar lines in 2011. Manufactured by Merz Pharmaceuticals.
- Botox: FDA-approved for cosmetic use in 2002. Manufactured by Allergan.
Key Differences
Formulation
- Xeomin: Contains only the active neurotoxin, free from accessory proteins. This “naked” formulation may reduce the risk of antibody development.
- Botox: Contains botulinum toxin type A with accessory proteins.
Onset and Duration
- Both products typically show results within 3–7 days.
- Duration of effect is similar, lasting about 3–4 months (individual results may vary).
Storage
- Xeomin is stable at room temperature before reconstitution, while Botox requires refrigeration.
Clinical Uses
- Both are FDA-approved for glabellar lines and used off-label for forehead lines, crow’s feet, and other areas.
Which Is Right for You?
The choice between Xeomin and Botox depends on individual factors, including medical history, previous response to neurotoxins, and personal preference. Some Patients may prefer Xeomin’s purified formulation, while others may have a history of successful results with Botox.
A consultation with an experienced Provider, such as Dr. Sherly Soleiman, MD, ensures a personalized approach based on your unique facial anatomy and goals.
Safety and Efficacy
Both Xeomin and Botox have well-established safety profiles when administered by trained medical professionals. Side effects are generally mild and temporary, including redness, swelling, or bruising at the injection site.
Conclusion
Xeomin and Botox are both effective options for reducing dynamic facial wrinkles. The best choice depends on your individual needs and should be determined in consultation with a board-certified physician.
Frequently Asked Questions
Is Xeomin as effective as Botox?
Clinical studies show similar efficacy and duration for both products, but individual results may vary.
Can I switch from Botox to Xeomin?
Yes, many Patients switch between products without issue. Your Provider will assess your suitability.
Are side effects different between Xeomin and Botox?
Both have similar side effect profiles, including mild redness or swelling at the injection site.
How do I know which product is best for me?
A consultation with Dr. Sherly Soleiman, MD, or a Master Injector at Cosmetic Injectables Center Medspa will help determine the best option for your goals.
Is Xeomin more “natural” than Botox?
Xeomin’s formulation is free from accessory proteins, but both products are purified and safe when administered by experienced Providers.